Dosage 2. Bullock L, Parks RB, Lampasona V, Mullins RE. 3. Infed should be injected only into the muscle mass of the upper outer quadrant of the buttock - never into the arm or other exposed areas - and should be injected deeply, with a 2-inch or 3-inch 19 or 20 gauge needle. Watson Pharma, Inc. INFeD (IRON DEXTRAN COMPLEX) INJECTION SDS EFFECTIVE DATE: SEPTEMBER 24, 2018 PAGE 1 OF 8 SAFETY DATA SHEET Prepared to U.S. OSHA, CMA, ANSI, Canadian WHMIS Standards, European Union CLP EC 1272/2008 and the Global Harmonization Standard 1. <> H|TMs6Wu*Q6i\l.` Delay administration of the initial therapeutic Infed dose until 1 hour or more after the test dose. Injection: 100 mg/2 mL (50 mg/1 mL), dark brown, slightly viscous, sterile solution in single-dose vials. Hatton RC, Portales IT, Finlay A, Ross EA. Administer test dose by intended route of administration for therapeutic doses prior to initial therapeutic dose. Indian J Anaesth. 12.2 Pharmacodynamics (See PRECAUTIONS: General.) NoPEF(djUMPU}ocl`<0yxk0R7?+9Ks,y the 6 time points after injection.15 A 94-subject rater-blinded randomized control study of EDP action potentials compared toxin used within 2 hours, 72 hours, 1, 2, 3, or 4 weeks after reconstitution; at 1 week after injection, the point of maximum effect, there was no difference in quantitative paralysis . Drug interactions involving Infed have not been studied. Allergan [2:/T6*cz1"Jk&n#n[[TU Before HdTn0D 0000007617 00000 n 0000024030 00000 n 0000001168 00000 n Adverse reactions experienced following administration of Infed may exacerbate cardiovascular complications in patients with pre-existing cardiovascular disease. CONTRAINDICATIONS P'q<48}*@Z@"M~5`9r8iH5H Aok1Tv=Yh4DU The etiology of these reactions is not known. Question patients regarding any prior history of reactions to parenteral iron products. Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. Risk of developing potentially life-threatening anaphylactic reactions. Hilleman DE, McEvoy GK, Bailey RT Jr, Reich J. Hosp Pharm. 2009;23(3):223-30. doi: 10.1080/15360280903098382. z6Y~]ZUkOR/R(;So__^41K}kf-#I{5mUirY@o"mkWbE *`CRM-uxbpRvIfKHrt/E(#|oU,NRSiH 0000047340 00000 n Bonnie E. Kirschenbaum, M.S., Clifton J. Latiolais, Sc.D., Stability of injectable medications after reconstitution, American Journal of Hospital Pharmacy, Volume 33, Issue 8, 1 August 1976, Pages 767791, https://doi.org/10.1093/ajhp/33.8.767. Copyright 1993-2021 [s Specific Populations 8600 Rockville Pike PDF 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE - Allergan %PDF-1.3 The formula shown below is based on the approximation that 1 mL of normocytic, normochromic red cells contains 1 mg of elemental iron: Replacement iron (in mg) = Blood loss (in mL) x hematocrit, Example: Blood loss of 500 mL with 20% hematocrit. Pharmacists should emphasize the importance of adhering to the storage conditions listed on the label after the medication is reconstituted.
